Free Thyroxine Measured by Equilibrium Dialysis and Nine Immunoassays in Sera with Various Serum Thy - roxine - binding
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چکیده
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منابع مشابه
Comparison of laboratory test results for assessing thyroid function in normal subjects and treated and untreated hyper- and hypothyroid patients.
Various indexes of thyroid status were measured in sera from normal men and women, normal women who were using oral contraceptives, hyper. and hypothyroid patients, and hypothyroid patients being successfully managed with various forms of replacement therapy. Total circulating thyroxine concentrations were measured by three methods as well as the thyroxine.binding capacity of the serum inter-al...
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A novel interference with measurements of serum free thyroxine (FT4) caused by rheumatoid factor (RhF) is described. We found misleading, sometimes gross, increases of FT4 results in 5 clinically euthyroid elderly female patients with high RhF concentrations. All 5 patients had high FT4 on Abbott AxSYM or IMx analyzers. "NETRIA" immunoassays gave misleading results in 4 of the 5 patients; Amerl...
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Considerable evidence suggests that the concentration of free thyroxine, circulating unbound to serum proteins, is more closely relattd to a subject's thyroidal status than is the concentration of total thyroxine (1). Because of the intense binding of thyroxine by the serum proteins, the concentration of free thyroxine is very small and not measurable by conventional chemical methods. Robbins a...
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